- September 19, 2006
It's astonishing how quickly a wide range of soy-based foods
and drinks has flooded our groceries and delis. Most consumers
are sure they are doing the right thing by replacing dairy with
soy products because they are so "health-promoting"
-- especially new mothers who are feeding their infants soy-based
formulas. However, there is a small group of nutrition experts
who strongly disagree about the so-called health properties of
soy. In fact, they fear soy might pose a danger to health, in
particular reproductive well-being. I wrote about these concerns
a number of months ago, but at that time large studies investigating
soy were not yet available. That has changed and the results have
taken many people by surprise.
By far the largest study was one done on mice at the National
Institutes of Health's Institute of Environmental Health Sciences.
It looked at genistein, one of the isoflavones (plant estrogen
substances also called phytoestrogens) contained in soy. For this
study, researchers injected genistein into groups of newborn female
mice at three different levels of dosages, all within the equivalency
of what a human baby might drink in soy-based formula. The mice
in all three groups showed disruption in the development of their
ovaries. As they matured, they had irregular menstrual cycles,
problems with ovulation and eventually with fertility. The mice
that received the highest dosage of genistein were infertile.
Those who received lower doses were sub-fertile, meaning they
had fewer pregnancies and fewer pups per litter. An NIH spokesperson
acknowledged that there was no way to know for certain how these
findings translate to humans, but they warrant caution. Another
spokesperson expressed the belief that the phytoestrogen would
likely affect these children as adults, if not in childhood.
The second startling study came from the American Heart Association,
which formed an expert committee to review a decade of randomized
studies on soy's benefits. This was especially important because
in 1999 the Food and Drug Administration (FDA) gave manufacturers
of soy-based foods permission to add labels that proclaimed these
foods to be heart-healthy based on studies that showed consuming
at least 25 grams of soy each day lowered cholesterol. Shortly
after that time, the AHA recommended making soy part of a heart-friendly
diet.
Now, some six years later, the AHA committee reviewed 22 studies
on dietary soy protein. The committee's findings: Consumption
of large amounts of soy protein has virtually no effect on LDL
levels, reducing them a mere 3%. Soy consumption does not raise
good cholesterol (HDL) at all, nor does it show any beneficial
effect on blood pressure. The committee also reviewed 19 studies
on soy isoflavones alone, which were supposedly associated with
relief of menopause symptoms. The review found that isoflavones
do not reduce menopause discomfort nor does soy protein.
Furthermore, the committee found that isoflavones do not help
prevent breast, uterine or prostate cancer. (The Solae Company,
which represents the industry, had already quietly withdrawn its
application to the FDA to label soy protein as having anti-cancer
benefits.) Or course these findings beg the question of what it
was that motivated the American Heart Association and the FDA
to so aggressively promote soy's benefits... but that's a subject
for a different article.
UNRAVELING THE CONFLICTING REPORTS
Clearly these findings are a striking blow against the common
beliefs about soy. To learn more about them and what was behind
the previously glowing reports of soy's benefits, I called Kaayla
Daniel, PhD, author of The Whole Soy Story: The Dark Side of America's
Favorite Health Food (New Trends). Dr. Daniel explains that much
of the previous research on soy (primarily funded by the soy industry)
was based on meta-analysis studies. For meta-analyses, researchers
gather a number of studies together on a given subject and average
out the congregate findings. Meta-analyses are valuable for providing
hints about what might be actually going on and suggestions for
appropriate follow-up randomized studies, but they are not considered
reliable last-word research.
The first weakness in meta-analyses is that researchers can cherry
pick among studies and by doing so influence findings, says Dr.
Daniel. And since findings are averaged out, a negative study
or two will be overwhelmed by favorable ones. Many years ago,
she says, there were some solid studies on soy, but they were
"put out to the field" in order to find ways to modify
the soy protein, what is left after oil is extracted from the
beans to turn it into acceptable animal feed. These studies investigated
what amino acids, fatty acids, vitamins and minerals should be
added to soy protein to make it safe and to protect reproductive
function. Dr. Daniel adds that the information gained from these
studies has not made its way to many of the soy-based products
that humans now eat.
The Soy That's in Our Food
To find out more about the soy that is in our food supply I called
Carolyn Dean, MD, ND, who has done extensive research on a number
of digestive-related topics and is author of IBS for Dummies (Wiley).
Dr. Dean points out that the wide varieties of soy-based foods
require extensive processing to get them to the state in which
they can be used as the foods now on our shelves -- they are far
from "natural." The beans are cooked, crushed and heated
to high temperatures and then put through a solvent extraction
process to remove the oil. The now defatted meal is mixed with
sugars and an alkaline solution to remove the fiber and the resulting
curds are spray dried at high temperatures, which does two things
-- produces high-protein powder... and peroxides the oils making
them pro-inflammatory. The end result is food that is bereft of
vitamins and likely minerals, she says, and far removed from being
a natural wholesome food. And there are other problems.
Because soy has a high level of phytic acid, it blocks digestion
of grains, which are an important source of minerals. Additionally,
soy contains trypsin inhibitors and these interfere with protein
digestion. Adding to these problems, the body does not absorb
the B-12 in soy, which in turn creates a nutritional void for
vegetarians who consume soy protein as a way of providing themselves
with this important B vitamin.
Even so, some soy products are reasonably healthy. Dr. Dean,
who also studied Chinese medicine, says that the Chinese did not
eat soy until they discovered that fermenting would turn it into
a useful food. In fact, fermented soy is largely the type of soy
that Asians consume today. Fermenting involves treating soy with
a mold for a day or so. Fermented foods include tempeh (not to
be confused with tofu, which is not fermented), which has a nutty
mushroom taste... miso... natto... and tamari sauce. However,
because soy exists in so many foods today as vegetable oil, binders
and the like, even people who are wary of soy probably consume
some of it almost daily. Consequently, Dr. Dean advises limiting
fermented soy product consumption to not more than every third
day.
The soy industry has ballooned in recent years and now represents
more than a billion dollars in sales per year. You can expect
to hear much more from both the industry and independent researchers
in the future concerning soy and health issues. I'll be sure to
keep you up to date. In the meanwhile, while searching your food
store for high-protein foods, take a pass on the ones "enriched
with soy protein."
Be well,
Carole Jackson
Bottom Line's Daily Health News
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Cure Memory Loss with Backyard Herb
Think you have memory challenges? Imagine memorizing all those
complex picture-characters in Japanese writing.
Maybe that's why hundreds of Japanese patients were so grateful
recently when a doctor reversed their short-term memory loss with
a simple tea made from eyebright -- an herb that you can grow
in your own garden.
While eyebright as a memory booster is new, its power to help
vision has been famous since the 14th century. It strengthens
the optic nerve, making the eye less vulnerable to cataracts.
This nerve-boosting also may help the brain, which, after all,
is made up of nerve cells.
Read on...
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Sources:
Bloom Is Off the Soy
Kaayla T. Daniel, PhD, author of The Whole Soy Story: The Dark
Side of America's Favorite Health Food (New Trends), and a board-certified
clinical nutritionist based in Santa Fe, New Mexico.
Carolyn Dean, MD, ND, author of IBS for Dummies (Wiley) and The
Miracle of Magnesium (Ballantine). She is in private practice
in New York City.
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